Table 3.

Patient age, serum albumin levels, and GFR at the four PK sampling periods posttransplant in 54 pediatric renal transplant recipients and the coefficients of correlation of these parameters with the respective MPA-AUC0–12 valuesa

Parameter1 wk3 wk3 mo6 mo
Mean ± SE (Range)CorrelationMean ± SE (Range)CorrelationMean ± SE (Range)CorrelationMean ± SE (Range)Correlation
a Data are mean ± SE (range).
Age (yr)11.1 ± 0.51r = 0.4011.1 ± 0.51r = 0.1111.3 ± 0.51r = 0.0611.6 ± 0.51r = 0.03
(3.17 to 16.0)P < 0.005(3.17 to 16.0)P = 0.45(3.42 to 16.3)P = 0.73(3.67 to 16.5)P = 0.86
Albumin (g/L)35.4 ± 0.99r = 0.4737.2 ± 0.84r = 0.0941.8 ± 0.84r = 0.3442.8 ± 0.62r = 0.31
(24.0 to 51.0)P < 0.005(27.0 to 53.0)P = 0.59(23.0 to 47.0)P = 0.052(36.0 to 47.0)P = 0.11
GFR (mL/min per62.6 ± 4.57r = 0.3380.1 ± 4.34r = 0.1284.8 ± 3.85r = 0.2884.1 ± 4.23r = 0.30
    1.73m2)(9.0 to 133)P < 0.04(14.0 to 143)P = 0.48(39.0 to 139)P = 0.09(45.0 to 123)P = 0.12