Table 2.

Allelic frequency of polymorphisms in the hKLK1 gene

VariantLocationPositionSubstitutionAllelic Frequency
NucleotideAmino AcidCaucasian (n = 46)African (n = 40)
a P < 0.05, compared with Caucasian subjects.
15′−128G→C0.290.31
25′−127G→C0.02
35′−123G→C0.01
45′−85C→T0.03
55′−19C→G0.040.14
6Intron 1Intron 1G→A0.01
7Exon 3+230G→AR→H (53)0.030.07a
8Exon 3+405C→TD→D (111)0.350.17a
9Exon 3+433C→GQ→E (121)0.330.35