Table 3.

Linkage disequilibrium between polymorphisms of the hKLK1 gene

Da
C−19GG230A (R53H)C405TC433G (Q121E)
a Calculations were performed by using contingency χ2 tests. Pairwise linkage was expressed as D′ = D/Dmax 33. D′ values of 1 or −1 depend on the disequilibrium with either the wild-type or mutated allele. Values close to 0 indicate the absence of disequilibrium between two polymorphisms. All values in this table are highly significant, except as indicated.
b Not significant.
G−128C−1−1−0.693b−0.519
C−19G1−1−1
G230A (R53H)−10.452b
C405T0.835