Table 1.

Changes in macula densa [Ca2+]i with ATP, P2 receptor antagonist, and phospholipase C inhibitora

GroupLumen/BathAgentsΔ[Ca2+]i (nM)n
a Values are mean ± SEM for n (number) of experiments. The concentration of ATP was 10−4 M.
b P < 0.01 versus group 2, 3, and 4.
1BathATP274 ± 32b27
2LumenATP2.4 ± 2.723
3Bath10−4 M suramin + ATP0.7 ± 1.97
4Bath10−6 M U-73122 + ATP1.8 ± 3.56
5Bath10−6 M U-73343 + ATP292 ± 38b9