Table 1.

Baseline characteristics at time of randomization, 6 mo after kidney transplantation. There are no statistically significant differences among the three groups

ParameterMMF/PredMMF/CsAMMF/CsA/Pred
a MMF, mycophenolate mofetil; CsA, cyclosporine; Pred, prednisone.
b Mean ± SD.
n patients637673
Age (yr)52 (20 to 72)52 (19 to 68)51 (19 to 70)
Female/male21/4224/5227/46
First/second graft57/668/864/9
Postmortal/living donor48/1558/1854/19
HLA mismatchesb
    HLA-A0.78 ± 0.660.87 ± 0.520.68 ± 0.53
    HLA-B0.90 ± 0.581.0 ± 0.650.66 ± 0.58
    HLA-DR0.71 ± 0.660.95 ± 0.600.67 ± 0.53
PRA >10%
    historical (%)433948
    recent (%)171323
Acute rejection ≤6 mo (biopsy-proven)10118
CsA
    dose (mg/d)b283 ± 102288 ± 85288 ± 84
    level (ng/ml)b160 ± 39158 ± 40158 ± 42