Table 2.

Series A: Early distal tubular flow rate (VED) and absolute and fractional reabsorption upstream to the early distal tubule (JED) of fluid and electrolyte in control and diabetic Sprague-Dawley rats on low- versus high-NaCl dieta

Control RatsDiabetic Rats
Low-NaCl (n = 66)High-NaCl (n = 79)Low-NaCl (n = 42)High-NaCl (n = 42)
a Data are mean ± SE; n, number of nephrons.
b P < 0.05 versus high-NaCl.
VED (nl/min)8 ± 17 ± 110 ± 1b8 ± 1
JED-fluid (nl/min)38 ± 137 ± 141 ± 2b35 ± 1
JED-Na+ (nmol/min)0.58 ± 0.020.55 ± 0.020.70 ± 0.02b0.57 ± 0.02
JED-CI (nmol/min)0.44 ± 0.010.42 ± 0.010.50 ± 0.01b0.39 ± 0.02
JED-K+ (pmol/min)194 ± 6203 ± 6175 ± 6163 ± 5
JED-fluid (%)83 ± 184 ± 180 ± 182 ± 1
JED-Na+ (%)95 ± 195 ± 196 ± 196 ± 1
JED-CI (%)96 ± 196 ± 197 ± 197 ± 1
JED-K+ (%)93 ± 194 ± 193 ± 194 ± 1