Table 3.

Effects of 17β-E2 in 1α-OHase-knockout micea

Control(n = 4)17β-E2(n = 4)
a 1α-OHase, 25-hydroxyvitamin D3-1α-hydroxylase; control, 1α-OHase-knockout mice;17β-E2, 1α-OHase-knockout mice supplemented with 10 μg 17β-E2/d; ND, not detectable. Data are presented as mean ± SEM.
bP < 0.05versus all (before and after).
Body weight (g)
    beginning15 ± 216 ± 1
    final15 ± 214 ± 1
Serum level
    17β-E2 (pg/ml)ND67 ± 12
    Ca2+ (mM), before1.54 ± 0.061.63 ± 0.06
    Ca2+ (mM), after1.69 ± 0.102.03 ± 0.12b