Table 2. Frequencies for EDN1 haplotypes consisting of T-1370G and K198N polymorphisms among subjects according to renal filtration status and microalbuminuria statusa

HaplotypeRenal Filtration StatusMicroalbuminuria Status
NomalDiminishedNomalMicroalbuminuria
a EDN1 indicates endothelin-1.
b P < 0.0001.
T-K0.7503 (0.0036)0.7443 (0.0222)0.7538 (0.0041)0.7373 (0.0103)
G-N0.0746 (0.0022)0.1816 (0.0196)b0.0716 (0.0024)0.0727 (0.0061)
T-N0.1602 (0.0031)0.0566 (0.0118)b0.1633 (0.0035)0.1727 (0.0089)
G-K0.0149 (0.0010)0.0175 (0.0067)0.0114 (0.0010)0.0174 (0.0031)