Table 4. Baseline patient characteristics associated with incident ischemic stroke, stratified by the presence of clinical CVDa

Prevalent CVDb (N = 3716, 330 Strokes)No Prevalent CVDb (N = 3146, 195 Strokes)
Adjusted Hazard Ratio (95% CI)
a Adjusted for DMMS study, age, gender, dialysis vintage, smoking history, height, and renal replacement modality (time-dependent - hemo-, peritoneal dialysis, or transplant), in an addition to the other covariates in this table. Patients with missing covariate values were excluded from the multivariate model.
b Prevalent CVD is defined as any of the following conditions at study start: coronary artery disease, myocardial infarction, coronary artery bypass, angioplasty, cardiac arrest, or congestive heart failure.
c Mean BP = (systolic BP + 2*diastolic BP)/3. BP measurements were taken predialysis (for hemodialysis patients) or randomly (for peritoneal dialysis patients).
Race
    whiteReferentReferent
    black0.77 (0.60–0.98)1.08 (0.79–1.47)
    Asian0.43 (0.16–1.17)0.59 (0.18–1.89)
    other0.60 (0.33–1.08)0.84 (0.43–1.64)
Markers of malnutrition
    undernourished1.40 (1.02–1.92)0.53 (0.28–1.00)
    serum albumin (1 g/dl decrease)1.30 (0.97–1.73)1.84 (1.28–2.64)
    weight (25% relative decrease)1.07 (0.95–1.21)1.04 (0.89–1.21)
Mean BP (10 mmHg increase)c1.03 (0.94–1.18)1.16 (1.04–1.30)
Renal disease
    primary GNReferentReferent
    hypertension1.30 (0.92–2.13)0.85 (0.54–1.35)
    diabetes1.63 (1.08–2.46)1.19 (0.75–1.89)
    PKD1.24 (0.77–2.00)0.67 (0.39–1.16)
    other0.79 (0.42–1.50)0.58 (0.28–1.18)