Table 3. Bone mineral density (BMD) at baseline and at the end of the study

Alfacalcidol (n = 20)Control (n = 20)P Value
Baseline12 moBaseline12 moPaPb
a Between groups at study entry.
b Between groups after 12 mo.
c Indicates a significant difference between time 0 and 12 mo (*P < 0.05; **P < 0.01).
BMD at lumber spine (g/cm2)1.1 ± 0.121.2 ± 0.111.1 ± 0.341.1 ± 0.300.070.44
BMD at lumber spine (SD below normal)−1.3 ± 0.9−1.1 ± 1.1c−1.3 ± 1.4−1.3 ± 0.50.180.003
BMD at lumber spine (% of normal BMD)85.6 ± 987.7 ± 681.7 ± 878.1 ± 5c0.770.05
BMD at femoral neck (g/cm2)0.94 ± 0.11.0 ± 0.02c0.93 ± 0.10.91 ± 0.10.480.26
BMD at femoral neck (SD below normal)−1.1 ± 1.0−0.3 ± 0.2c−0.9 ± 1.0−1.1 ± 0.70.180.05
BMD at femoral neck (% of normal BMD)87.3 ± 689.1 ± 2c85.3 ± 981.5 ± 7c0.360.01
BMD at forearm (g/cm2)0.7 ± 0.120.9 ± 0.14c0.7 ± 0.120.7 ± 0.040.690.03
BMD at forearm (SD below normal)−1.4 ± 0.8−0.7 ± 0.1−1.3 ± 1.0−1.3 ± 0.40.450.001
BMD at forearm (% of normal BMD)83.6 ± 986.8 ± 584.8 ± 985 ± 70.360.45