Table 1. Serum and urine biochemical analysis of serum and urine from osteopontin (OPN) knockout and wild-type mice

ParameterGenotypeBaseline2 wk4 wk
a P < 0.05 compared with OPN wild-type group at the same time point.
Serum Ca2+ (mg/dl)KO9.4 ± 0.09ND9.5 ± 0.13
Serum Ca2+ (mg/dl)WT9.4 ± 16ND9.8 ± 0.15
Serum P042− (mg/dl)KO7.2 ± 0.36ND8.2 ± 0.58
Serum P042− (mg/dl)WT7.5 ± 0.24ND7.7 ± 0.49
Urine Ca2+ (mg/dl)KO3.9 ± 0.56.3 ± 1.14.7 ± 0.6
Urine Ca2+ (mg/dl)WT6.3 ± 1.14.8 ± 0.65.2 ± 0.9
Urine P042− (mg/dl)KO180 ± 26a182 ± 51280 ± 33
Urine P042− (mg/dl)WT329 ± 30253 ± 49294 ± 42
Urinary citrate (mmol/L)KO4.4 ± 1.73.7 ± 1.65.2 ± 2.3
Urinary citrate (mmol/L)WT4 ± 1.12.5 ± 0.92.1 ± 1.4
Urinary oxalate (mg/L)KO38 ± 8.9169 ± 29308 ± 78
Urinary oxalate (mg/L)WT56 ± 13.8149 ± 55285 ± 58