Table 2. Levels of proximal and distal tubular cell proliferation and apoptosis at 4 wk in osteopontin (OPN) knockout and wild-type (WT) micea

ParameterOPN WTOPN KOP
a Data are presented as mean ± SEM. hpf, high-power field.
BrDU-positive proximal tubular cells/10 hpf6.55 ± 3.265.59 ± 2.060.8
BrDU-positive distal tubular cells/10 hpf1.3 ± 0.551.31 ± 0.520.99
TUNEL-positive proximal tubular cells/10 hpf0.55 ± 0.080.92 ± 0.610.6
TUNEL-positive distal tubular cells/10 hpf0.3 ± 0.090.17 ± 0.080.288