Table 1. Baseline patient characteristics and subsequent outcomes by creatinine production quartiles

1st Quartile UCR < 0.57 (n = 272)2nd Quartile 0.57 ≤ UCR < 0.78 (n = 266)3rd Quartile 0.78 ≤ UCR < 1.00 (n = 262)4th Quartile ≥ 1.00 (n = 274)P value
a Malnutrition was defined as the presence of clinical diagnosis of malnutrition, serum albumin ≤25th percentile (≤2.9), or body mass index ≤10th percentile (≤19.25).
b Within each creatinine production quartile, MDRD GFR was significantly different from creatinine clearance using a paired t test (P < 0.001).
Demographics
    age, mean ± SD, yr66 ± 1464 ± 1462 ± 1456 ± 15<0.001
    male gender, n (%)111 (41)93 (35)122 (47)182 (66)<0.001
    African-American ethnicity, n (%)66 (24)56 (21)59 (23)78 (28)0.223
    Medicare insurance, n (%)190 (70)167 (63)147 (56)114 (42)<0.001
Comorbid conditions
    diabetes cause of renal failure, n (%)125 (46)118 (44)111 (42)132 (48)0.722
    coronary artery disease, n (%)135 (50)119 (45)116 (44)97 (35)0.001
    congestive heart failure, n (%)136 (50)99 (37)104 (40)84 (31)<0.001
    cerebrovascular accident, n (%)43 (16)31 (12)37 (14)30 (11)0.182
    peripheral vascular disease, n (%)72 (26)57 (21)51 (19)39 (14)<0.001
    left ventricular hypertrophy, n (%)78 (29)57 (21)71 (27)49 (18)0.019
    smoker within past year, n (%)94 (35)85 (32)101 (39)101 (37)0.304
    AIDS, n (%)3 (1.1)2 (.8)1 (.4)7 (2.6)0.174
Functional status
    requires assistance to eat, n (%)12 (4)3 (1)7 (3)4 (1)0.077
    requires assistance to transfer, n (%)56 (21)31 (12)24 (9)15 (5)<0.001
Nutritional parameters
    body mass index, mean ± SD24.5 ± 5.725.3 ± 5.826.0 ± 5.726.5 ± 5.1<0.001
    serum albumin, mean ± SD, g/dl3.2 ± 0.73.3 ± 0.63.3 ± 0.63.4 ± 0.7<0.001
    malnutritiona, n (%)130 (48)90 (34)83 (32)72 (26)0.001
Renal function parameters
    blood urea nitrogen, mean ± SD, mg/dl87.0 ± 30.883.5 ± 30.384.0 ± 28.589.6 ± 30.30.062
    serum creatinine, mean ± SD, mg/dl5.8 ± 2.66.3 ± 2.26.7 ± 1.98.6 ± 3.1<0.001
    MDRD GFR, mean ± SD, ml/minb10.9 ± 4.69.5 ± 3.38.9 ± 2.87.6 ± 2.4<0.001
    creatinine clearance, mean ± SD, ml/minb5.8 ± 2.98.3 ± 2.49.8 ± 2.711.3 ± 3.4<0.001
    urine creatinine, mean ± SD, g/24 h0.42 ± 0.130.68 ± 0.060.88 ± 0.061.32 ± 0.34
Outcomes during follow-up
    transplantation, n (%)13 (5)13 (5)23 (9)49 (18)<0.001
    death, n (%)153 (56)132 (50)110 (42)66 (24)<0.001