Table 2. Comparison of patients with sepsis who did and did not develop ARF on the first day of sepsisa

Patients without ARFPatients with ARFP
a Values (highest (H) or lowest (L)) are recorded during the first day of sepsis, and are expressed as median (interquartile range). ARF, acute renal failure; MAP, mean arterial BP; CVP, central venous pressure; PAC, pulmonary artery catheter; PAOP, pulmonary artery occlusion pressure; NOR, dosage of norepinephrine; WBC, white blood cell count. P values in bold are significant.
Hemodynamic data
    heart rate (/min) (H)110 (94.0 to 123.3)113 (97.3 to 124.8)0.556
    MAP (mmHg) (L)72 (63.0 to 81.5)66 (57.0 to 70.3)0.004
    CVP (mmHg) (L)5 (3.0 to 8.0)8 (4.0 to 13.0)0.008
    patients with PAC (%)44 (28.4%)13 (43.3%)0.105
    PAOP (mmHg) (L)6 (4.0 to 8.0)9 (5.0 to 12.5)0.074
    CO (L/min) (L)6.4 (5.60 to 8.05)7.2 (4.60 to 8.50)0.771
    vasoactive therapy (%)56 (36.1%)17 (56.7%)0.035
    NOR (μg/kg per min) (H)0.22 (0.13 to 0.28)0.17 (0.09 to 0.32)0.664
Ventilatory data
    ventilatory support (%)113 (72.9%)24 (80.0%)0.417
    PaO2/FIO2 (L)208 (120.0 to 278.0)121 (95.0 to 161.5)0.003
    PaO2 (mmHg) (L)92 (73 to 124)76 (63 to 91)0.014
    PaCO2 (mmHg) (L)33 (30 to 38)37 (31 to 46)0.028
Hematologic data
    WBC count (103/mm3) (H)14.7 (10.7 to 19.2)16.3 (11.8 to 20.3)0.347
    hematocrit (%) (L)30.5 (25.9 to 35.3)27.9 (24.3 to 32.0)0.028
    platelet count (103/mm3) (H)182 (114 to 252)159 (116 to 217)0.252
Biochemistry data
    Na+ (mmol/L)139 (135 to 141)137 (134 to 142)0.492
    K+ (mmol/L)3.6 (3.4 to 4.0)3.9 (3.5 to 4.3)0.068
    glycemia (g/dl) (H)1.63 (1.43 to 2.08)1.79 (1.27 to 2.73)0.612
    urea (mg/dl) (H)40 (20 to 50)55 (40 to 162.5)<0.001
    creatinine (mg/dl) (H)0.91 (0.75 to 1.05)1.43 (1.05 to 2.4)<0.001
    AST (U/L)35 (20 to 78)37 (24 to 93)0.286
    pH (L)7.37 (7.33 to 7.42)7.27 (7.19 to 7.33)<0.001
    HCO3 (mmol/L) (L)22 (20 to 24)19 (17 to 24)0.027
Fluid management
    volume balance (L/24 h)1.0 (0.05 to 1.84)2.1 (1.52 to 3.12)<0.001
    urinary volume (L/24 h)1.6 (0.92 to 2.33)0.9 (0.44 to 1.41)<0.001