Table 3. Spontaneous cytokine expression in subjects (mean ± SD)a

T Cell Subset/cytokine ExpressionNormal Controls (n = 14) (%)Good Responders (n = 14) (%)Poor Responders (n = 18) (%)One-Way ANOVA Variance ratio (F), Probability (P)
a PBMC were taken prior to dialysis session and cultured for 18 h before cytokine determination by flow cytometry.
b P < 0.05 and c P < 0.01 for poor responders versus good responders.
d P < 0.05 and e P < 0.01 for poor responders versus normal controls.
CD8/IFN-γ0.3 ± 0.30.2 ± 0.30.6 ± 0.8F = 2.661
P = 0.0820
CD4/IFN-γ0.1 ± 0.20.3 ± 0.70.2 ± 0.3F = 0.717
P = 0.4943
CD8/TNF-α0.3 ± 0.30.4 ± 0.41.5 ± 1.2ceF = 9.179
P = 0.0005
CD4/TNF-α0.7 ± 1.10.4 ± 0.50.7 ± 0.6F = 0.651
P = 0.5269
CD8/IL-40.4 ± 0.40.4 ± 0.40.5 ± 0.8F = 0.298
P = 0.7439
CD4/IL-40.3 ± 0.50.2 ± 0.20.3 ± 0.3F = 0.533
P = 0.6389
CD8/IL-100.4 ± 0.40.9 ± 1.82.4 ± 3.0dF = 3.700
P = 0.0333
CD4/IL-100.1 ± 0.10.2 ± 0.30.5 ± 0.2beF = 7.262
P = 0.0020
CD8/IL-130.2 ± 0.40.1 ± 0.20.7 ± 1.1F = 3.293
P = 0.0472
CD4/IL-130.1 ± 0.30.1 ± 0.10.1 ± 0.2F = 1.429
P = 0.2512