Table 2. Two-point LOD scores for the linked and other candidate regions of FSGS and AS genes

11q24 Locus MarkersRecombination Fraction (θ)
00.050.10.150.20.250.30.350.40.45
D11S2002−4.07−0.140.290.450.510.510.460.380.280.15
D11S2000−5.5−1.31−0.79−0.51−0.35−0.23−0.14−0.08−0.03−0.01
D11S1986−4.971.461.521.451.321.140.920.680.430.2
D11S908−4.071.341.411.351.221.060.860.640.410.19
D11S1998−4.271.691.741.641.491.281.040.780.50.23
D11S44600.340.310.280.250.210.180.140.110.070.04
D11S9251.341.221.10.970.850.720.590.450.310.2
D11S44642.021.811.61.41.190.990.790.60.40.2
D11S13280.880.790.70.610.530.440.360.270.180.09
D11S934−2.830.030.340.460.490.470.420.330.230.12
D11S1304−2.99−0.130.20.340.390.390.360.30.220.12
D11S9691.631.471.31.140.970.810.650.490.330.17
Other LociMarkersLOD at θ = 0Genes
1q25D1S1677−4.03Nephrosis 2 (NPHS2: PODOCIN)
D1S15890.26
D1S518−4.3
2q35–q37D2S1363−6.11Collagen, type IV, alpha 3 (COL4A3)
D2S427−2.14Collagen, type IV, alpha 4 (COL4A4)
9q34D9S2157−1.2LIM homeobox transcription factor 1, beta (LMX1B)
D9S18250.003
13q33–q34D13S895−2.91Collagen, type IV, alpha 1 (COL4A1)
D13S285−4.66Collagen, type IV, alpha 2 (COL4A2)
19q13D19S245−2.97Actinin, alpha 4 (ACTN4)
22q11.2D22S683−4.33Myosin, heavy polypeptide 9, non-muscle (MYH9)
D22S1045−4.21