Table 5. Effect of randomization group and 7 predefined clinical variables on infection-related hospitalization and death rate

ParameterRate of Inf Hospitalizationsb (1698 Events)Inf Deathsc (201 Events)
RR95% CIRR95% CI
a ICED, Index of Coexisting Disease.
b The effect of the randomized treatment intervention on this outcome was evaluated using overdispersed Poisson regression analysis while controlling for the seven prespecified baseline covariates listed.
c The effect of the randomized treatment intervention on this outcome was evaluated using Cox regression analysis, stratified by clinical center and controlling for the seven prespecified baseline covariates listed, as well as the interaction between baseline serum albumin and follow-up time. The relative risk for the interaction term was 1.21 (95% CI, 1.06 to 1.38), indicating that there was a progressive weakening of the effect of baseline albumin over time, with its relative risk alternative toward 1.0 by 21% per year of followup.
d P < 0.001.
High-Kt/V group0.95(0.83 to 1.09)0.99(0.75 to 1.31)
High-flux group0.93(0.81 to 1.07)0.85(0.64 to 1.13)
Age (per 10 yr)1.01(0.95 to 1.07)1.47d(1.29 to 1.68)
Diabetic1.45d(1.24 to 1.69)1.26(0.93 to 1.72)
Baseline albumin (per 0.5 g/dl)0.73d(0.66 to 0.82)0.43d(0.29 to 0.64)
Baseline comorbidity score (per ICED unit)a1.25d(1.14 to 1.37)1.46d(1.21 to 1.76)
Black race1.04(0.87 to 1.24)0.84(0.59 to 1.18)
Gender (female)1.03(0.89 to 1.20)1.00(0.74 to 1.36)
Years dialysis1.01(1.00 to 1.03)1.04(1.00 to 1.07)