Table 2. Renal function and BP

Cyclosporine (n = 60)Tacrolimus (n = 64)
Baseline3 Mo6 MoBaseline3 Mo6 Mo
Mean ± SD or median and interquartile range.
* P < 0.05;
P < 0.01;
P < 0.001 for comparison with baseline. Dynamap BP was determined in 84 patients from three participating centers.
Serum creatinine (μmol/l)143 ± 48147 ± 48146 ± 53137 ± 30136 ± 32131 ± 29
Proteinuria (g/24 hr)0.200.220.200.14
(0.10–0.52)(0.11–0.70)(0.08–0.50)(0.08–0.44)
Body weight (kg)75.0 ± 14.074.8 ± 14.377.8 ± 15.876.5 ± 15.1
BP manually
    mean (mmHg)102 ± 10104 ± 11104 ± 11104 ± 1399 ± 12101 ± 13
    systolic (mmHg)140 ± 15144 ± 18142 ± 18144 ± 21138 ± 18140 ± 21
    diastolic (mmHg)83 ± 984 ± 1085 ± 1084 ± 1280 ± 1182 ± 10
BP Dynamap
    mean (mmHg)105 ± 13105 ± 11106 ± 10106 ± 14101 ± 9102 ± 11
    systolic (mmHg)141 ± 17142 ± 14144 ± 14141 ± 19135 ± 15137 ± 18
    diastolic (mmHg)83 ± 982 ± 983 ± 982 ± 1079 ± 879 ± 9
No. of antihypertensive drugs1.9 ± 1.01.9 ± 1.02.0 ± 1.02.1 ± 1.12.0 ± 1.12.2 ± 1.1