Table 4. Glucose, parameters of fibrinolysis, and plasma homocysteine

Cyclosporine (n = 60)Tacrolimus (n = 64)
Baseline3 Mo6 MoBaseline3 Mo6 Mo
Mean ± SD or median and interquartile range.
* P < 0.05,
P < 0.01,
P < 0.001 for comparison with baseline.
# Determined in all patients from one center (17 cyclosporine patients and 18 tacrolimus patients). tPA, tissue type plasminogen; PAI-I, plasminogen activator inhibitor type I.
Glucose (mmol/L)5.5 ± 1.55.3 ± 1.25.2 ± 1.15.4 ± 1.35.8 ± 1.9*5.6 ± 1.8
    nondiabetic5.1 ± 0.65.0 ± 0.85.1 ± 0.75.1 ± 0.95.4 ± 0.85.3 ± 1.0
    diabetic8.6 ± 2.97.4 ± 2.16.4 ± 2.58.0 ± 1.99.2 ± 4.48.9 ± 3.4
HbA1c (%)5.6 ± 0.55.6 ± 0.55.6 ± 0.45.8 ± 0.96.1 ± 1.76.1 ± 1.4
    nondiabetic#5.5 ± 0.45.6 ± 0.45.5 ± 0.35.6 ± 0.45.5 ± 0.55.6 ± 0.5
    diabetic7.9 ± 0.67.6 ± 0.67.6 ± 0.78.8 ± 1.79.2 ± 1.28.5 ± 1.0
Fibrinogen (mg/L)3543 ± 6793569 ± 6813637 ± 7083638 ± 8573367 ± 7633417 ± 751*
tPA (ng/mL)3.80 ± 15.683.29 ± 1.423.22 ± 1.374.07 ± 2.713.65 ± 1.783.68 ± 2.04
PAI-I (ng/ml)26.82 ± 15.6833.23 ± 20.7834.95 ± 19.1330.04 ± 20.5730.38 ± 17.6831.65 ± 18.29
tPA-PAI complex (ng/ml)8.38 ± 4.778.20 ± 4.037.77 ± 4.5610.19 ± 7.429.53 ± 6.379.79 ± 6.57
uPA (ng/ml)1.22 ± 0.371.27 ± 0.411.23 ± 0.401.26 ± 0.351.17 ± 0.37*1.16 ± 0.33*
Homocysteine (μmol/l)18.6 (16.3–22.1)19.0 (14.6–21.6)18.1 (14.5–21.2)18.4 (14.7–23.7)18.0 (13.9–24.7)16.6 (14.6–21.1)