Table 1. Renal pathology

ParameterSHAM (n = 7)ADX (n = 7)ADX + Ang II (n = 6)ADX + ALDO (n = 8)
Values are mean ± SEM.
a P < 0.05, b P < 0.01 compared with SHAM.
c P < 0.05, d P < 0.01 compared with ADX.
e P < 0.05, f P < 0.01 compared with ADX + Ang II.
TMA
    Glomerular (%)14.3 ± 2.60.6 ± 0.6b1.8 ± 1.6b8.2 ± 1.7a,d,e
        Thrombotic (%)2.9 ± 0.30.2 ± 0.2b0.1 ± 0.1b1.8 ± 0.9c,e
        Ischemic (%)11.4 ± 2.40.4 ± 0.4b1.7 ± 1.6b6.4 ± 1.1a,c,e
    Vascular (%)20.2 ± 2.21.4 ± 1.4b2.7 ± 2.7b15.1 ± 2.9d,f
Ischemic tubules (%)35 ± 33 ± 3b2 ± 2b27 ± 7d,f
Tubular casts (%)3.4 ± 0.80.1 ± 0.1b0.3 ± 0.3b3.4 ± 0.6d,f