Table 4. Multivariable Cox regression models of all-cause death and cardiovascular death with body-mass index (BMI) and urinary creatinine (UCr) as continuous variables in the entire cohort and in BMI subgroupsa

ModelAll-Cause DeathCardiovascular Death
Hazard Ratio (95% CI)P valueHazard Ratio (95% CI)P value
a Each model adjusted for age, gender, race, Medicare insurance, comorbid condition, functional status, and serum albumin levels.
All patients (n = 70,028)
    each 5 kg/m2 increase in BMI0.95 (0.93 to 0.96)<0.0010.95 (0.94 to 0.97)<0.001
    each g/d increase in UCr0.68 (0.65 to 0.70)<0.0010.67 (0.64 to 0.71)<0.001
18.5 ≤BMI <25 (n = 34,046)
    each 5 kg/m2 increase in BMI0.87 (0.83 to 0.91)<0.0010.91 (0.85 to 0.96)0.001
    each g/d increase in UCr0.70 (0.66 to 0.74)<0.0010.68 (0.63 to 0.73)<0.001
25 ≤BMI <30 (n = 20,598)
    each 5 kg/m2 increase in BMI0.94 (0.87 to 1.01)0.0970.90 to 0.81 to 1.00)0.055
    each g/d increase in UCr0.68 (0.63 to 0.73)<0.0010.67 (0.61 to 0.74)<0.001
BMI ≥30 (n = 15,384)
    each 5 kg/m2 increase in BMI1.04 (1.01 to 1.07)0.0211.02 (0.98 to 1.07)0.317
    each g/d increase in UCr0.67 (0.62 to 0.73)<0.0010.69 (0.62 to 0.78)<0.001