Table 1. Candidate gene variants in human DNP

Gene Name	Gene Symbol	Gene Variant	Chromosome	Reference
Histocompatibility antigen	HLA	DR3/4	6	51
Angiotensin-converting enzyme	ACE	D/I	17	17, 20
Angiotensinogen	AGT	M235T	1	52
Angiotensin II type I receptor	AT1R	A1166C	3	53, 54
Aldose reductase	ALR2	Z + 2 allele	7	22
Heparan sulphate	HSPG2	BamHI	1	55
Apolipoprotein E	APOE	e2 allele	19	56
Paraoxonase 1	PON1	T107C, Leu54Met,	7	57
Endothelial cell nitric oxide	NOS3	’a’ allele	7	58
Methylenetetrahydrofolate reductase	MTHFR	C677T	1	59
Interleukin 1β	IL1B	T105C	2	60
Atrial natriuretic peptide	NPPA	Hpall (C708T and Scal)	1	61
G-protein β 3	GPB3	C834T/Trp64Arg	12	62
Ecto-nucleotide pyrophosphatase/phosphodiesterase	ENPP1	K121Q	6	63
Glucose transporter1	GLUT1	Xbal/HaeIII	1	64
Transforming growth factor β1	TGFB1	Leu10Pro, Arg25Pro, Thre263Ile	19	65