Table 1. Influence of angiotensin II (AngII) stimulation on glucosaminoglycan composition
| ECM | Culture Supernatant | |||
|---|---|---|---|---|
| Medium | AngII | Medium | AngII | |
| The results of three independent experiments are depicted as mean % of total glycosaminoglycans (GAG) ± SD. Percentages were calculated from the total amount of GAG, based on 35S-incorporation, that was susceptible to HNO2 treatment. Significant differences between medium and AngII in the mean % of heparan sulfate proteoglycans (HSPG) were found in the extracellular matrix (ECM) (P < 0.05) but not culture supernatant. | ||||
| HSPG | 74.0 ± 2.7a | 66.3 ± 2.3 | 42.9 ± 4.4 | 45.2 ± 7.6 |
| Non-HSPG | 26.0 ± 2.7 | 37.7 ± 2.3 | 57.1 ± 4.4 | 54.8 ± 7.6 |