Table 1. Effects of 4 weeks of a high-salt diet on body weight, left ventricular weight, and urine volume, urinary excretion of sodium, potassium, and NOx; and renal cortical collagen and thiobarbituric acid reactive substances contents in Dahl salt-resistant and Dahl salt-sensitive ratsa

DR RatsDS Rats
Low SaltHigh SaltLow SaltHigh SaltHigh Salt + TempolHigh Salt + Hydralazine
a Values are means ± SE. DR, Dahl salt-resistant; DS, Dahl salt-sensitive; LVW, left ventricular weight; UV, urine volume; UNaV, urinary excretion of sodium; UKV, urinary excretion of potassium; UNOxV, urinary excretion of NOx; TBARS, thiobarbituric acid reactive substances.
b P < 0.05 versus same strain on low-salt diet.
c P < 0.05: DS rats/high-salt diet versus DS rats/high-salt diet + tempol or hydralazine.
Body weight (g)327 ± 2326 ± 4339 ± 2336 ± 3341 ± 2340 ± 4
LVW (g/100 g body wt)0.19 ± 0.020.20 ± 0.040.22 ± 0.030.38 ± 0.03b0.26 ± 0.04c0.27 ± 0.06c
UV (ml/d)10 ± 166 ± 3b13 ± 290 ± 6b68 ± 5bc78 ± 3bc
UNaV (mEq/d)1.3 ± 0.426.7 ± 1.2b0.9 ± 0.124.3 ± 1.4b24.0 ± 1.9b27.7 ± 0.7b
UKV (mEq/d)1.0 ± 0.14.1 ± 0.1b1.2 ± 0.14.2 ± 0.2b3.7 ± 0.2b4.2 ± 0.2b
UNOxV (μmol/d)0.22 ± 0.010.45 ± 0.02b0.18 ± 0.020.21 ± 0.030.37 ± 0.02bc0.15 ± 0.02
Collagen content (μg/g)12 ± 215 ± 113 ± 123 ± 1b14 ± 1c19 ± 1bc
TBARS (nmol/g)31 ± 330 ± 441 ± 6108 ± 9b48 ± 8c72 ± 6bc