Table 3. Calculated GFR (Nankivell method, mL/min) at month 36 in patients with or without a primary biopsy-proven acute rejection (includes values after discontinuation)

Time of RejectionRejectionSRL-CsA-ST (n = 215)SRL-ST (n = 215)ANCOVA P Value
a Mean ± SEM.
b Number of observations used to calculate the mean. GFR set to zero for graft loss.
c Includes both on-therapy period after randomization and follow-up after discontinuation periods.
d Any primary rejection from the time of transplantation.
PrerandomizationNo48.4 ± 1.9a (176)b60.3 ± 1.9 (174)<0.001
Yes36.6 ± 5.8 (18)51.6 ± 5.7 (20)0.028
PostrandomizationcNo48.7 ± 1.9 (183)61.3 ± 1.9 (177)<0.001
Yes23.2 ± 6.6 (11)39.5 ± 5.9 (17)0.060
PosttransplantationdNo49.9 ± 1.9 (166)62.6 ± 1.9 (158)<0.001
Yes31.9 ± 4.6 (28)45.4 ± 4.2 (36)0.017