Table 3. Associations between baseline characteristics and septicemia hospitalization in the first year of dialysis therapy in the 1996-to-1999 cohort
Factor | Relative Riska | 95% CIa,b | Pa |
---|---|---|---|
a Using a Poisson regression model including the variables shown in the first column. The reference categories were peritoneal dialysis; age 20 to 44 yr; male gender; other race; non-Hispanic ethnicity; 1996 as year of dialysis inception; absence of congestive heart failure, atherosclerotic heart disease, cardiac arrest or dysrhythmia, stroke or transient ischemic attack, peripheral vascular disease, chronic obstructive pulmonary disease, current tobacco use, cancer, alcohol or drug dependence, inability to ambulate or transfer; hemoglobin 11 to 12 g/dl; serum albumin 3.1 to 3.4 g/dl; estimated GFR 5.1 to 10 ml/min per 1.73 m2; and body mass index 18.5 to 24.9 kg/m2. | |||
Mode of dialysis | |||
hemodialysis | 2.09 | 1.97 to 2.22 | <0.0001 |
peritoneal dialysis | 1 | — | — |
Age (yr) | |||
0 to 19 | 0.71 | 0.59 to 0.86 | 0.0003 |
20 to 44 | 1 | — | — |
54 to 64 | 0.85 | 0.81 to 0.89 | <0.0001 |
65 to 74 | 1.02 | 0.98 to 1.07 | 0.4 |
≥75 | 1.21 | 1.15 to 1.26 | <0.0001 |
Gender | |||
male | 1 | — | — |
female | 1.02 | 0.99 to 1.05 | 0.09 |
Race | |||
white | 0.97 | 0.90 to 1.03 | 0.3 |
black | 1.07 | 0.99 to 1.14 | 0.06 |
Asian | 0.61 | 0.55 to 0.68 | <0.0001 |
other | 1 | — | — |
Hispanic ethnicity | 1.09 | 1.05 to 1.13 | <0.0001 |
Congestive heart failure | 1.14 | 1.11 to 1.18 | <0.0001 |
Atherosclerotic heart disease | 0.98 | 0.95 to 1.01 | 0.1 |
Cardiac arrest or dysrhythmia | 1.02 | 0.97 to 1.07 | 0.5 |
Stroke or transient ischemic attack | 1.16 | 1.11 to 1.21 | <0.0001 |
Peripheral vascular disease | 1.11 | 1.08 to 1.15 | <0.0001 |
Diabetes | 1.11 | 1.08 to 1.14 | <0.0001 |
Chronic obstructive pulmonary disease | 1.09 | 1.05 to 1.15 | <0.0001 |
Current tobacco use | 0.95 | 0.90 to 1.00 | 0.06 |
Cancer | 1.20 | 1.14 to 1.27 | <0.0001 |
Alcohol or drug dependence | 1.18 | 1.09 to 1.28 | <0.0001 |
Inability to ambulate or transfer | 1.65 | 1.57 to 1.73 | <0.0001 |
Hemoglobin (g/dl) | |||
<11 | 1.05 | 1.01 to 1.09 | 0.03 |
11 to 12 | 1 | — | — |
>12 | 0.99 | 0.93 to 1.06 | 0.9 |
Serum albumin (g/dl) | |||
≤3.0 | 1.24 | 1.20 to 1.28 | <0.0001 |
3.1 to 3.4 | 1 | — | — |
≥3.5 | 0.84 | 0.80 to 0.87 | <0.0001 |
Estimated GFR (ml/min per 1.73 m2) | |||
<5 | 0.89 | 0.86 to 0.93 | <0.0001 |
5 to 10 | 1 | — | — |
>10 | 1.22 | 1.19 to 1.26 | <0.0001 |
Body mass index (kg/m2) | |||
<18.5 | 1.18 | 1.13 to 1.24 | <0.0001 |
18.5 to 24.9 | 1 | — | — |
25 to 29.9 | 0.95 | 0.92 to 0.98 | 0.0007 |
≥30 | 1.01 | 0.97 to 1.04 | 0.68 |