Table 1. Baseline characteristics by level of estimated creatinine clearance among women enrolled in HERSa

Creatinine clearance (ml/min per 1.73 m2)
≥60 (n = 1275)30–59 (n = 1438)<30 (n = 44)
a MI, myocardial infarction; CABG, coronary artery bypass graft; PTCA, percutaneous transluminal angioplasty.
b P ≤ 0.05.
c P ≤ 0.01.
d P ≤ 0.001.
Age ± SD (yr)63 ± 670 ± 6d71 ± 5d
Race
    white (%)889073c
    black (%)8825d
    other (%)43c2
Untreated diabetes97b8
Treated with oral agent108c23*
Treated with insulin9916
Hypertension (%)6770b93d
Mean LDL cholesterol ± SD (mg/dl)147 ± 40143 ± 36c149 ± 46
Mean HDL cholesterol ± SD (mg/dl)49 ± 1251 ± 14d51 ± 17
Median lipoprotein(a) level (25th–75th percentile range)24 (7 to 53)27 (7 to 56)26 (8 to 60)
Mean triglyceride level ± SD (mmHg)168 ± 63164 ± 63b190 ± 72b
Mean body mass index ± SD (kg/m2)31 ± 627 ± 5d28 ± 5d
Current smoker (%)1611d21
Aspirin use at baseline (%)807857d
HMG-CoA reductase inhibitor use at baseline (%)363741
Estrogen progestin treatment group (%)514948
Any alcohol use in last 30 d (%)423932
Exercise646530d
Average number of prior MI0.60.60.8b
Percent prior CABG3844c52
Percent prior PTCA4641b34