Table 2. Semiquantitative scores of histological analysis

Sham4d RK4d RK + ARB7d RK7d RK + ARBExtended RK
a P < 0.05 versus sham.
b P < 0.05 versus matched time point RK (Mann-Whitney U test).
PAS
    Tubular atrophy0.3 ± 0.10.3 ± 0.20.3 ± 0.20.4 ± 0.10.4 ± 0.10.9 ± 0.2a
    Interstitial infiltration0.1 ± 0.10.1 ± 0.10.1 ± 0.10.2 ± 0.10.2 ± 0.11.0 ± 0.1a
Trichrome Masson
    Interstitial expansion0.1 ± 0.10.2 ± 0.10.2 ± 0.10.1 ± 0.10.1 ± 0.11.3 ± 0.2a
    Pimonidazole adduction0.6 ± 0.22.6 ± 0.4a0.9 ± 0.3b3.1 ± 0.3a1.4 ± 0.6b3.0 ± 0.2a
    Vimentin0.1 ± 0.10.1 ± 0.10.1 ± 0.10.1 ± 0.10.1 ± 0.10.4 ± 0.1a
    α-SMA0 ± 0.10.1 ± 0.10.1 ± 0.10.1 ± 0.10.1 ± 0.10.2 ± 0.1