Table 2. Thirty-day mortalitya

Variable% NMean (SD)Univariate AnalysisAdjusted for Crea GroupsMultivariate Analysis
HR (95% CI)P ValueHR (95% CI)P ValueHR (95% CI)P Value
a HR, hazard ratios; CI, confidence interval; BL, baseline; ACE, angiotensin-converting enzyme; DHCA, deep hypothermic cardiac arrest; EC, erythrocyte concentrate suspension; FFP, fresh frozen plasma; RRT, postoperative renal replacement therapy.
b Mortality according to the logistic model.
Group Δ−−53.95 (2.23–6.96)0.0001(−)2.27 (1.28–4.03)0.0052
Group Δ−54111
Group Δ+362.77 (1.94–3.95)0.0001(−)1.92 (1.34–2.77)0.0004
Group Δ++518.64 (12.8–27.13)0.0001(−)5.76 (3.86–8.61)0.0001
Risk indicators
    BL serum creatinine (mg/dl)2.78 (2.22–3.49)0.00011.82 (1.42–2.33)0.0001NS
    Weight (pro 10 kg)77 (14)0.84 (0.76–0.92)0.00030.81 (0.73–0.89)0.0001NS
    EuroSCOREb (mortality %)7.6 (8.8)1.05 (1.04–1.06)0.00011.04 (1.03–1.05)0.0001NS
    log (EuroScore)2.45 (2.12–2.82)0.00012.07 (1.79–2.4)0.00011.62 (1.4–1.89)0.0001
    angina stable310.55 (0.4–0.77)0.0005NSNS
    congestive heart failure162.51 (1.88–3.36)0.00011.89 (1.41–2.54)0.0001NS
    diabetes211.50 (1.11–2.02)0.0083NSNS
    hypertension (<140/90 mmHg)420.69 (0.52–0.91)0.0098NSNS
    hypertension (>140/90 mmHg)10NSNSNS
    smoker140.42 (0.25–0.73)0.0018NSNS
Medication
    diuretics331.92 (1.47–2.51)0.00011.73 (1.32–2.27)0.00011.57 (1.19–2.06)0.0014
    ACE inhibitors43NSNSNS
Perioperative data
    anesthesia (h)319 (84)1.44 (1.35–1.53)0.00011.27 (1.19–1.35)0.0001NS
    surgery (h)227 (77)1.47 (1.38–1.57)0.00011.28 (1.2–1.37)0.0001NS
    CPB (h)115 (54)1.48 (1.37–1.61)0.00011.33 (1.21–1.46)0.0001NS
    aortic cross-clamp (h)72 (32)1.51 (1.24–1.83)0.00011.32 (1.1–1.58)0.0033NS
    DHCA (h)30 (16)3.39 (1.34–8.58)0.0099NSNS
    urgent surgery122.92 (2.16–3.96)0.00011.99 (1.46–2.72)0.0001NS
    reoperation <1 mo1.1NSNSNS
    resternotomy ≤48 h3.13.39 (2.14–5.38)0.00011.95 (1.22–3.12)0.0051NS
    resternotomy >48 h7.42.19 (1.49–3.20)0.0001NSNS
    IABP after CPB2.86.95 (4.75–10.18)0.00013.78 (2.55–5.59)0.00011.75 (1.17–2.63)0.0068
    inotropics after CPB363.62 (2.73–4.81)0.00012.74 (2.05–3.66)0.00011.55 (1.15–2.10)0.0044
    urinary output (L)0.7 (0.5)NSNSNS
    crystalloids (L)2.3 (1.1)NSNSNS
    colloids (L)0.6 (0.4)1.79 (1.3–2.46)0.00031.61 (1.19–2.17)0.0021NS
    EC (units)1.5 (2)1.27 (1.23–1.3)0.00011.19 (1.15–1.22)0.00011.10 (1.07–1.14)0.0001
    FFP (units)0.7 (2)1.19 (1.16–1.22)0.00011.14 (1.11–1.17)0.0001NS
    platelets (units)0.1 (0.3)3.01 (2.55–3.55)0.00011.91 (1.60–2.28)0.0001NS
    assist device0.423.4 (12.38–44.24)0.00019.78 (5.12–18.7)0.0001NS
    RRT5.712.61 (9.57–16.61)0.00016.95 (5.1–9.48)0.00014.77 (3.53–6.45)0.0001