Table 2. Renal function and urinary protein excretion in C57BL/6 WT, IL-12p40−/−, and IFN-γ−/− mice with EAGa
| Serum Creatinine (μmol/L) | Urinary Protein (mg/24 h) | |
|---|---|---|
| a Results are expressed as the mean ± SEM. EAG, experimental autoimmune glomerulonephritis; GN, glomerulonephritis. | ||
| b P < 0.01 versus other three groups (ANOVA). | ||
| c Results in this group exclude two oligoanuric mice. | ||
| Normal mice no GN | 10.9 ± 1.0 | 1.2 ± 0.3 |
| C57BL/6 WT GN | 12.9 ± 1.0 | 2.6 ± 0.3b |
| IL-12p40−/− GN | 10.9 ± 1.2 | 1.4 ± 0.1 |
| IFN-γ−/− GN | 27.3 ± 11.2 | 1.4 ± 0.4c |