Table 2. Renal function and urinary protein excretion in C57BL/6 WT, IL-12p40−/−, and IFN-γ−/− mice with EAGa

Serum Creatinine (μmol/L)Urinary Protein (mg/24 h)
a Results are expressed as the mean ± SEM. EAG, experimental autoimmune glomerulonephritis; GN, glomerulonephritis.
b P < 0.01 versus other three groups (ANOVA).
c Results in this group exclude two oligoanuric mice.
Normal mice no GN10.9 ± 1.01.2 ± 0.3
C57BL/6 WT GN12.9 ± 1.02.6 ± 0.3b
IL-12p40−/− GN10.9 ± 1.21.4 ± 0.1
IFN-γ−/− GN27.3 ± 11.21.4 ± 0.4c