Table 1. Baseline characteristics by category of estimated creatinine clearancea

Estimated CrCl (ml/min)
≥90 (N = 349)75–89 (N = 222)60–74 (N = 125)<60 (N = 34)
a CrCl, creatinine clearance; BMI, body mass index; MI, myocardial infarction.
b Continuous variables are presented as means ± SD.
Age (yr)b57.6 ± 6.861.7 ± 5.563.7 ± 4.465.4 ± 3.3
Creatinine (mg/dl)0.6 ± 0.10.8 ± 0.10.9 ± 0.11.2 ± 0.3
BMI (kg/m2)27.1 ± 5.525.0 ± 4.024.4 ± 3.924.1 ± 5.1
Physical activity (metabolic h/wk)14 ± 1515 ± 1716 ± 1814 ± 17
Hemoglobin A1C (g/dl)5.9 ± 1.25.9 ± 0.95.9 ± 1.15.9 ± 0.9
Total cholesterol (mg/dl)226 ± 41228 ± 39239 ± 39233 ± 44
HDL (mg/dl)56 ± 1760 ± 1659 ± 1755 ± 22
Diabetes (%)11%12%7%21%
Hypertension (%)37%36%45%50%
Current smoker (%)35%29%30%26%
Parental history of MI at age 60 or less (%)17%14%11%24%