Table 2. Unadjusted mean and SD of inflammatory biomarkers by category of estimated CrCla

BiomarkerEstimated CrCl (ml/min)
≥90 (N = 349)75–89 (N = 222)60–74 (N = 125)<60 (N = 34)
To convert mg/L to mg/dl, divide by 10.
a hs-CRP, high-sensitivity C-reactive protein; sTNFR, soluble tumor necrosis factor receptor; ICAM, intracellular adhesion molecule; VCAM, vascular cell adhesion molecule.
b P ≤ 0.05 compared with estimated CrCl <60 subgroup.
hs-CRP (mg/l)4.5 ± 5.64.0 ± 4.64.5 ± 5.56.5 ± 7.8
E-selectin (ng/ml)50.4 ± 24.447.4 ± 24.746.0 ± 2050.7 ± 17.2
Fibrinogen (mg/dl)349 ± 88351 ± 98367 ± 99364 ± 104
Homocysteine (μmol/l)10.3 ± 3.3b11.3 ± 7.5b11.9 ± 4.213.6 ± 5.8
ICAM-1 (ng/ml)283 ± 89b278 ± 111b280 ± 89b319 ± 84
IL-6 (pg/ml)2.4 ± 2.8b2.6 ± 3.5b2.6 ± 2.44.3 ± 6.2
Pyridoxal 5′-phosphate (ng/ml)60.9 ± 87.480.4 ± 168.067.1 ± 80.460.6 ± 68.7
sTNFR I (pg/ml)1230 ± 343b1284 ± 378b1478 ± 419b2104 ± 1004
sTNFR II (pg/ml)2414 ± 691b2539 ± 664b2797 ± 785b4024 ± 1553
VCAM-1 (ng/ml)668 ± 163b665 ± 143b708 ± 153b816 ± 193