Table 2. Risk factors for being hospitalized for sepsis in the first year of chronic hemodialysis, including timing of permanent access creation

Risk FactorGroup% (n = 5924)Hazard RatioP-value95% CI
The number of hospitalizations for sepsis was 483 (8.20%).
a Comorbidity score is the Charleson-Deyo index modified by subtracting the renal disease and diabetes components.
b 2nd Access creation is defined as a time-dependent covariate.
The relative risks of sepsis in the Early access creation and the Just prior access creation groups were 0.48 (95% CI, 0.35 to 0.65) and 0.72 (95% CI, 0.54 to 0.95), respectively, if catheter use was not included in the model.
Access timingWithin 1 month prior/after62.21.00
1 to 4 mo prior16.80.820.197(0.61 to 1.11)
>4 mo prior20.90.57<.001(0.41 to 0.79)
Catheter use70.11.410.012(1.08 to 1.84)
Age at start of dialysis (yr)<5024.41.00
50 to 6428.50.850.196(0.66 to 1.09)
65 to 7428.90.870.284(0.68 to 1.12)
75+18.30.860.287(0.64 to 1.14)
GenderMale63.01.220.043(1.01 to 1.48)
Access typeFistula80.21.00
Graft19.81.260.038(1.01 to 1.55)
Started dialysis as inpatient51.51.280.022(1.04 to 1.57)
Diabetes45.81.340.002(1.12 to 1.61)
Comorbidity scorea047.5
121.90.990.902(0.77 to 1.26)
216.11.160.265(0.90 to 1.50)
3+14.51.140.361(0.87 to 1.49)
2nd access creationb34.11.230.079(0.98 to 1.55)