Table 3. Plasma acid-base parameters of control animals in response to bosentana

pHPCO2 (mmHg)Calculated [HCO3] (mM)Measured [TCO2] (mM)
a Values are means ± SEM.
20% protein (control) week 1 (n = 8)7.41 ± 0.0239.2 ± 1.024.1 ± 0.925.2 ± 0.6
20% protein (+bosentan) week 1 (n = 8)7.40 ± 0.0238.9 ± 0.923.7 ± 0.624.8 ± 0.6
20% protein (+bosentan) week 3 (n = 8)7.39 ± 0.0239.8 ± 1.023.6 ± 0.724.5 ± 0.5
20% protein (+bosentan) week 3 (n = 8)7.40 ± 0.0238.2 ± 0.923.1 ± 0.624.1 ± 0.5