Table 4. Plasma acid-base parameters of HiPro animals in response to bosentana

pHPCO2 (mmHg)Calculated [HCO3] (mM)Measured [TCO2] (mM)
a Values are means ± SEM.
b P < 0.05 versus HiPro.
50% protein (HiPro) week 1 (n = 8)7.37 ± 0.0239.1 ± 1.022.0 ± 0.723.1 ± 0.6
50% protein (+bosentan) week 1 (n = 8)7.34 ± 0.0236.1 ± 1.119.0 ± 0.919.9b ± 0.5
50% protein (+bosentan) week 3 (n = 8)7.38 ± 0.0238.3 ± 1.022.2 ± 0.623.0 ± 0.5
50% protein (+bosentan) week 3 (n = 8)7.37 ± 0.0237.6 ± 1.021.3 ± 0.622.2 ± 0.5