Table 3. Blood pressure, glomerular filtration and urinary excretion of NCC+/+ (n = 7) and NCC−/− (n = 7) mice
| NCC+/+ | NCC−/− | |
|---|---|---|
| a P < 0.05. | ||
| Values are means ± SEM. | ||
| Body wt (g) | 27.2 ± 0.5 | 28.0 ± 0.6 |
| Mean arterial pressure (mmHg) | 99 ± 3 | 97 ± 3 |
| GFR (μl/min/g bw) | 6.0 ± 0.5 | 4.3 ± 0.3a |
| Na+-filtered (μmol/min/g bw) | 0.91 ± 0.09 | 0.66 ± 0.04a |
| K+-filtered (nmol/min/g bw) | 38 ± 3 | 26 ± 3a |
| Ca2+-filtered (nmol/min/g bw) | 11.0 ± 0.1 | 7.6 ± 0.6a |
| Urinary flow (nl/min/g bw) | 79 ± 14 | 52 ± 8 |
| Urinary Na+ excretion (nmol/min/g bw) | 5.5 ± 1.1 | 2.9 ± 0.6a |
| Urinary K+ excretion (nmol/min/g bw) | 8.6 ± 1.1 | 6.7 ± 0.7 |
| Urinary Ca2+ excretion (pmol/min/g bw) | 29 ± 7 | 12 ± 3a |