Table 1.

Characteristics of patients in the studya

VariableAKI(n = 52)No AKI(n = 86)P
Age (mean ± SD)50 ± 18.650.4 ± 160.9
Male gender42.3%58.1%0.07
Ethnicity0.07
    white non-Hispanic73.1%73.3%
    black non-Hispanic21.2%17.4%
    Hispanic0.0%7.0%
    other5.8%2.3%
Precipitating factor0.005
    trauma5.8%24.4%
    sepsis30.8%15.1%
    pneumonia44.2%36%
    aspiration5.8%15.1%
    other13.5%9.3%
Nonpulmonary or renal organ failure0.4
    1 other organ42.3%33.7%
    2 other organs32.7%30.2%
    3 other organs7.7%8.1%
    4 other organs3.8%3.5%
APACHE III (mean ± SD)77 ± 2073 ± 250.3
Pao2/Fio2 < 20084.6%74.4%0.15
Vasopressors53.8%30.2%0.006
Systolic BP (mmHg; mean ± SD)97 ± 27102 ± 230.25
Ventilation protocol0.5
    6 ml/kg52%57%
    12 ml/kg48%43%
Renal characteristics (day 0)
    median serum creatinine (mg/dl; range)0.85 (0.5 to 1.1)0.90 (0.5 to 1.1)0.3
    median urine output (L; range)1.9 (0.7 to 4.5)2.5 (1.4 to 5.8)0.004
Fractional excretion of sodium (%)1.06 ± 1.61.12 ± 1.60.8
Mortality
    28-d mortality57.7%19.8%<0.0001
    180-d mortality63.5%25.6%<0.0001
  • a AKI, acute kidney injury; APACHE, Acute Physiologic Assessment and Chronic Health Evaluation.