Table 4.

Hazard ratio of death for ferritin categories based on time-dependent Cox regression modelsa

UnadjustedCase-Mix AdjustedCase-Mix and MICS Adjusted
HR (95% CI)P ValueHR (95% CI)P ValueHR (95% CI)P Value
All to cause death ferritin range
    <500.81 (0.70 to 095)0.0090.74 (0.63 to 0.87)<0.0010.84 (0.72 to 0.99)0.04
    50 to 991.02 (0.90 to 1.15)0.80.90 (0.8 to 1.02)0.090.93 (0.82 to 1.05)0.3
    100 to 199 (reference)1.00NA1.00NA1.00NA
    200 to 2990.94 (0.86 to 1.03)0.200.97 (0.89 to 1.07)0.50.94 (0.86 to 1.04)0.22
    300 to 4990.89 (0.82 to 0.93)0.0050.93 (0.86 to 1.00)0.060.87 (0.80 to 0.94)<0.001
    500 to 6490.93 (0.86 to 1.01)0.091.006 (0.926 to 1.094)0.90.95 (0.87 to 1.03)0.21
    650 to 7990.93 (0.85 to 1.01)0.080.95 (0.872 to 1.035)0.240.87 (0.80 to 0.95)0.001
    800 to 9991.13 (1.04 to 1.23)0.0060.99 (0.91 to 1.07)0.70.89 (0.82 to 0.97)0.01
    1000 to 11991.32 (1.20 to 1.44)<0.0011.07 (0.97 to 1.17)0.180.90 (0.82 to 0.99)0.02
    1200 to 14991.67 (1.53 to 1.83)<0.0011.32 (1.20 to 1.44)<0.0011.05 (0.96 to 1.15)0.3
    1500 to 19992.31 (2.09 to 2.56)<0.0011.59 (1.43 to 1.76)<0.0011.13 (1.02 to 1.25)0.02
    ≥20003.00 (2.65 to 3.39)<0.0011.78 (1.57 to 2.01)<0.0011.16 (1.02 to 1.32)0.02
CV death ferritin range
    <500.80 (0.63 to 1.01)0.060.73 (0.58 to 0.93)0.010.81 (0.64 to 1.03)0.09
    50 to 991.08 (0.90 to 1.30)0.40.97 (0.81 to 1.16)0.71.0 (0.83 to 1.20)1.0
    100 to 199 (reference)1.00NA1.00NA1.00NA
    200 to 2990.96 (0.84 to 1.1)0.60.99 (0.86 to 1.14)0.90.97 (0.84 to 1.11)0.6
    300 to 4990.89 (0.79 to 1.00)0.060.92 (0.82 to 1.04)0.18350.88 (0.78 to 0.99)0.04
    500 to 6490.97 (0.86 to 1.10)0.61.05 (0.92 to 1.19)0.51.00 (0.89 to 1.14)1.0
    650 to 7990.95 (0.84 to 1.08)0.40.99 (0.87 to 1.12)0.80.91 (0.80 to 1.04)0.15
    800 to 9991.11 (0.98 to 1.27)0.090.98 (0.87 to 1.12)0.80.91 (0.80 to 1.04)0.16
    1000 to 11991.26 (1.09 to 1.45)0.0021.04 (0.9 to 1.19)0.60.90 (0.78 to 1.03)0.13
    1200 to 14991.64 (1.43 to 1.88)<0.0011.33 (1.16 to 1.53)<0.0011.10 (0.96 to 1.27)0.18
    1500 to 19992.09 (1.78 to 2.45)<0.0011.50 (1.28 to 1.77)<0.0011.13 (0.96 to 1.33)0.16
    ≥20002.55 (2.09 to 3.12)<0.0011.67 (1.36 to 2.04)<0.0011.15 (0.93 to 1.41)0.189
  • a HR, hazards ratio; CI, confidence interval; MICS, malnutrition-inflammation complex syndrome; NA, not applicable.