Table 1.

Semiquantitative analysis of histologic and immunochemical studiesa

CharacteristicVehicle-TreatedDXS-Treated
PAS-positive score
    glomerular1.49 ± 0.23b0.56 ± 0.15
    tubular1.31 ± 0.23c0.59 ± 0.15
Fibrin glomerular thrombus formation score1.46 ± 0.250.80 ± 0.14
Glomerular endothelial score1.85 ± 0.12c2.97 ± 0.14
  • a DXS, dextran sulfate; PAS, periodic acid-Schiff.

  • b P < 0.001 vehicle-treated versus DXS-treated group.

  • c P < 0.01 vehicle-treated versus DXS-treated group.\