Table 2.

Densitometric analysis of ENaC expression (12-wk experiment, protocol 1)a

Control(n = 7)Cirrhosis(n = 10)
Cortex/OSOM
    α-ENaC100 ± 4%98 ± 4%
    β-ENaC100 ± 10%50 ± 11%b
    γ-ENaC 85 kD100 ± 9%38 ± 6%b
    γ-ENaC 70 kD100 ± 11%171 ± 77%
ISOM
    α-ENaC100 ± 8%82 ± 10%
    β-ENaC100 ± 22%41 ± 10%b
    γ-ENaC 85 kD100 ± 6%64 ± 5%b
    γ-ENaC 70 kD100 ± 22%428 ± 156%b
Inner medulla
    α-ENaC100 ± 4%99 ± 7%
    β-ENaC100 ± 17%24 ± 16%b
    γ-ENaC 85 kD100 ± 5%73 ± 10%b
    γ-ENaC 70 kD100 ± 9%123 ± 28%
  • a Values are expressed as mean ± SE. ENaC, epithelial sodium channel; OSOM, outer stripe of the outer medulla; ISOM, inner stripe of the inner medulla.

  • b P < 0.05 versus control.