Table 6.

Densitometric analysis of sodium transporter expression (12-wk experiment, protocol 1)a

Control(n = 7)Cirrhosis(n = 10)
Cortex/OSOM
    Na,K-ATPase α1100 ± 19%145 ± 10%
    NHE3100 ± 9%71 ± 4%b
    NKCC2100 ± 19%138 ± 22%
    NCC100 ± 19%145 ± 15%
ISOM
    Na,K-ATPase α1100 ± 15%126 ± 19%
    NHE3100 ± 10%174 ± 16%b
    NKCC2100 ± 15%179 ± 16%b
Inner medulla
    Na,K-ATPase α1100 ± 7%89 ± 6%
  • a Values are expressed as mean ± SE. NHE3, type 3 Na/H exchanger; NKCC2, Na-K-2Cl co-transporter; NCC, thiazide-sensitive Na-Cl co-transporter.

  • b P < 0.05 compared with control.