Table 3.

Renal biopsy findings in patients with ARF after treatment with OSPS bowel purgativea

PatientNo. of GlomeruliNo. of Sclerotic GlomeruliTubular InjuryTubular Calcium Phosphate% TA and IFInterstitial InflammationVascular DiseaseHistopathologic Pattern
1535DiffuseDiffuse30%MildModerateA/C TIN
23015DiffuseDiffuse40%MildModerateA/C TIN
3474DiffuseDiffuse60%MinimalModerateA/C TIN
4b61MildDiffuse50%ModerateModerateA/C TIN, NDGS
5222DiffuseDiffuseNoneMinimalNoneATN
6191MildDiffuse25%MildMildA/C TIN
7202MildDiffuse60%ModerateSevereA/C TIN
8329MildDiffuse60%MildSevereA/C TIN
9172DiffuseDiffuse30%ModerateModerateA/C TIN
10c91MildDiffuse60%ModerateSevereA/C TIN, segmental MG
11161MildDiffuse50%MinimalModerateA/C TIN
12162DiffuseDiffuse10%MildModerateATN
13172MildDiffuse60%MildModerateA/C TIN
14322DiffuseDiffuse5%MinimalMildATN
15176MildDiffuse70%MildModerateA/C TIN
16194MildDiffuse70%ModerateModerateA/C TIN
17132MildDiffuse40%MildModerateA/C TIN
18171MildDiffuse20%MinimalModerateA/C TIN
19203MildDiffuse15%MinimalMildA/C TIN
20161DiffuseDiffuseNoneMinimalMildATN
21402MildDiffuse60%MildModerateA/C TIN
  • a TA and IF tubular atrophy and interstitial fibrosis; A/C TIN, acute and chronic tubulointerstitial nephropathy; NDGS, nodular diabetic glomerulosclerosis; ATN, acute tubular necrosis; NA, not available; MG, membranous glomerulopathy.

  • b Patient 4 also had biopsy findings of mild nodular diabetic glomerulosclerosis.

  • c Patient 10 also had biopsy findings of rare segmental subepithelial deposits, seen only by electron microscopy, consistent with segmental MG.