Table 1.

Baseline characteristics of patients with iMN (n = 57)a

Gender (M/F)38/19
Age (yr)48 ± 16
MAP (mmHg)98 ± 16
ECC-24 h (ml/min per 1.73 m2)88 ± 26
Serum creatinine (mg/dl)1.00 ± 0.23
Serum β2m (mg/L)2.8 ± 1.1
Serum albumin (g/dl)2.4 ± 0.5
Cholesterol (mg/dl)329 ± 76
Interval Bx measurement (mo)2 (0–33)
Follow-upb (mo)53 ± 23
Timed urine sample:
    albumin excretion (mg/min)3.8 (0.3–16)
    IgG excretion (mg/24 h)197 (18–3597)
    β2m excretion (μg/min)c0.38 (0.05–68.4)
    α1m excretion (μg/min)29 (4–418)
    transferrin excretion (μg/min)283 (17–1455)
    selectivity index0.18 (0.06–0.39)
    proteinuria (g/g creatinine)5.8 (1.7–13.3)
  • a Data are means ± SD or medians (range). IMN, idiopathic membranous nephropathy; MAP, mean arterial pressure; ECC 24 h, creatinine clearance calculated from 24 h urine; β2m, β2-microglobulin; Bx, renal biopsy.

  • b From baseline measurement until end of follow-up.

  • c In case of β2m excretion: n = 56; in one patient, β2m was not measurable because pH urine was too low (<6.0).