Table 3.

Associations between prevalent CHD, CHD mortality, and microalbuminuria

EuropeansSouth AsiansAfrican Caribbeansa
MenWomenaMenWomenaMenWomen
Microalbuminuria: Odds ratios for association with prevalent CHDb
    nc1015 (119 cases)443 (25 cases)738 (76 cases)205 (3 cases)283 (15 cases)275 (12 cases)
    unadjusted1.43 (0.71 to 2.89)6.20 (1.57 to 24.52)2.71 (1.29 to 5.73)0.89 (0.11 to 7.08)No CHD cases had microalbuminuria
    adjusted for age1.29 (0.63 to 2.63)7.16 (1.75 to 29.31)2.39 (1.11 to 5.14)0.80 (0.10 to 6.45)
    adjusted for age and smoking status1.21 (0.60 to 2.55)6.72 (1.62 to 27.9242.49 (1.15 to 5.39)0.75 (0.09 to 6.11)
    adjusted for age and glucose tolerance category1.12 (0.54 to 2.32)7.11 (1.72 to 29.3)2.20 (1.01 to 4.82)0.68 (0.08 to 5.67)
    adjusted for age and SBPd1.37 (0.66 to 2.83)8.29 (1.92 to 35.76)2.25 (1.03 to 4.91)0.62 (0.07 to 5.25)
    adjusted for age, smoking status,e glucose tolerance category,f and SBPd1.09 (0.52 to 2.28)6.17 (1.43 to 26.54)1.93 (0.87 to 4.26)0.68 (0.08 to 5.60)
Microalbuminuria: Hazard ratios for association with CHD mortalityc
    nc1017 (59 deaths)445 (9 deaths)743 (47 deaths)206 (1 death)a283 (4 deaths)a276 (1 death)a
    unadjusted1.89 (0.81 to 4.39)10.79 (2.24 to 52.0)3.01 (1.35 to 6.72)
    adjusted for current age1.75 (0.75 to 4.08)13.01 (2.63 to 64.2)2.47 (1.10 to 5.52)
    adjusted for current age and baseline CHDc1.89 (0.81 to 4.41)2.14 (0.94 to 4.89)
    adjusted for current age and smoking statuse1.78 (0.77 to 4.14)2.45 (1.09 to 5.48)
    adjusted for current age and glucose tolerance categoryf1.52 (0.65 to 3.60)2.31 (1.03 to 5.20)
    adjusted for current age and SBPd1.56 (0.67 to 3.64)2.03 (0.90 to 4.59)
    adjusted for age, smoking status,e glucose tolerance category,f and SBPd1.41 (0.60 to 3.34)1.90 (0.94 to 4.31)
  • a South Asian women excluded because of the small numbers of cases with prevalent CHD or deaths caused by CHD. African Caribbeans were excluded from mortality analyses because of small numbers of deaths caused by CHD. European women: mortality analyses limited to age adjustment only.

  • b Prevalent CHD defined by doctor-diagnosed angina or heart attack and/or the presence of major Q waves or LBBB on ECG. Because of the small number of CHD deaths, analyses in European women were limited to adjustment for current age.

  • c Number available for analysis (some participants did not have sufficient data to establish presence of CHD). CHD deaths defined by International Classification of Diseases, Ninth Revision codes 410 to 4149 or International Classification of Diseases, Tenth Revision codes I200 to I259

  • d Quartiles of SBP (treated hypertension ranked in upper quartile).

  • e Smoking status: current, former, never.

  • f Normoglycemia, impaired fasting glucose/impaired glucose tolerance, and diabetes (World Health Organization 1999 criteria [22]).