Table 1.

Characteristics of those with and without noncardiovascular mortalitya

AliveNon-CVD DeathCVD DeathP Valueb
N3344785533
Age74 ± 577 ± 677 ± 6<0.001
Race (black)597 (18%)116 (15%)89 (17%)0.12
Gender (female)2104 (63%)371 (47%)243 (46%)<0.001
Smoking<0.001
    never1602 (49%)271 (35%)208 (40%)
    former1396 (43%)399 (52%)247 (47%)
    current283 (8%)100 (13%)69 (13%)
Diabetes423 (13%)149 (19%)149 (28%)<0.001
Prevalent CVD699 (21%)237 (30%)260 (49%)<0.001
Physical activityc945 (1700)608 (1390)615 (1463)<0.001
Weight (lb)161 ± 32157 ± 34160 ± 320.02
CRP (mg/L)c2.54 ± 4.442.84 ± 5.753.55 ± 6.44<0.001
Hemoglobin (g/dl)13.7 ± 1.413.5 ± 1.613.7 ± 1.4<0.001
WBC count (1000/mm3)6.2 ± 1.86.9 ± 6.66.8 ± 2.2<0.001
3MSE score92 ± 887 ± 1386 ± 13<0.001
Systolic BP136 ± 20136 ± 23141 ± 23<0.001
Diastolic BP72 ± 1171 ± 1271 ± 140.022
FEV1 (L)2.13 ± 0.651.95 ± 0.682.00 ± 0.68<0.001
Carotid IMT (mm)1.05 ± 0.211.13 ± 0.261.18 ± 0.27<0.001
AAI1.11 ± 0.161.05 ± 0.220.97 ± 0.24<0.001
Creatinine (mg/dl)0.97 ± 0.291.14 ± 0.531.15 ± 0.60<0.001
Cystatin C (mg/L)1.06 ± 0.251.27 ± 0.481.29 ± 0.50<0.001
eGFR (ml/min per 1.73 m2)73 ± 1767 ± 2166 ± 20<0.001
  • a CVD, cardiovascular disease; CRP, C-reactive protein; WBC, white blood cell; 3MSE, Modified Mini-Mental Status; FEV1 forced expiratory volume in 1 s; AAI, ankle-arm index; eGFR, estimated GFR.

  • b Significance values (<0.05) indicate that at least one of the groups differs from the others.

  • c Median (interquartile range), Kruskal Wallis Test.