Table 3.

Cause-specific mortality rates per 1000 person-years by quartile of kidney functiona

Quartile 1 (No. of Events), RateQuartile 2 (No. of Events), RateQuartile 3 (No. of Events), RateQuartile 4 (No. Events), RateP Valueb
Cystatin C
    dementia(22) 2.7(25) 3.2(24) 2.9(41) 6.1<0.001
    pulmonary disease(9) 1.1(11) 1.4(19) 2.3(28) 4.2<0.001
    infection(7) 0.9(12) 1.5(21) 2.6(47) 7.0<0.001
    cancer(75) 9.2(70) 8.9(79) 9.7(134) 19.9<0.001
    other(25) 3.1(16) 2.1(33) 4.1(87) 12.9<0.001
    total non-CVD(138) 16.8(134) 17.1(176) 21.6(337) 50.0<0.001
    CVD mortality(56) 6.9(86) 11.0(150) 18.4(241) 35.8<0.001
eGFR
    dementia(21) 2.7(22) 2.7(26) 3.3(43) 6.1<0.001
    pulmonary disease(22) 2.8(11) 1.4(12) 1.5(22) 3.1<0.001
    infection(12) 1.5(15) 1.8(21) 2.7(39) 5.5<0.001
    cancer(90) 11.4(73) 9.0(76) 9.7(119) 16.7<0.001
    other(25) 3.2(26) 3.2(33) 4.2(77) 10.8<0.001
    total non-CVD(170) 21.6(147) 18.1(168) 21.5(300) 42.2<0.001
    CVD mortality(99) 12.6(111) 13.6(124) 15.9(199) 28.0<0.001
  • a The values for cystatin C are <0.93, 0.93 to 1.04,1.05 to 1.22, and >1.22 mg/L; the values for eGFR are >81.43, 81.43 to 70.08, 70.07 to 60.17, and <60.17,

  • b Test for linear trend.