Table 6.

Bias, precision, and accuracy of creatinine and cystatin C estimates for patients with estimated GFR <60 and ≥60 ml/min per 1.73 m2 a

GFRNBiasPrecisionAccuracy % Within
10%30%
Estimates using creatinine
    Cockcroft-Gault
        <6072−4.012.91976
        ≥6045−1.614.64287
    abbreviated MDRD
        <6090−10.512.62068
        ≥6027−8.314.53793
    original MDRD
        <6092−11.711.61564
        ≥6025−10.814.22888
    Walser
        <6097−12.514.11557
        ≥6020−11.115.24085
    Jelliffe
        <60103−15.115.81548
        ≥6014−11.016.05093
    Mawer
        <6051−4.014.52469
        ≥606621.324.51550
    Nankivell
        <60680.012.03273
        ≥6049−3.414.74188
Estimates using cystatin C
    Filler
        <6065−0.99.63185
        ≥6052−2.613.45690
    Le Bricon
        <6070−0.39.73687
        ≥6047−8.813.05191
    Larsson
        <60100−16.913.1849
        ≥6017−11.519.81276
    Hoek
        <6088−8.69.62680
        ≥6029−16.415.21779
  • a Bias was defined as the mean difference between measured (

  • 99 Tc-DTPA) and estimated GFR; precision was defined as the SD of the difference between measured (

  • 99 Tc-DTPA) and estimated GFR. Both precision and bias were expressed as ml/min per 1.73 m

  • 2 ; accuracy was defined as the proportion of values that were within 10 or 30% of the measured (

  • 99 Tc-DTPA) GFR.