Table 1.

Descriptive statistics for baseline parameters by baseline renal function and diabetic status in patients who had or were at high risk for coronary diseasea

No CKD NondiabeticCKD NondiabeticNo CKD DiabeticCKD Diabetic
N141944099873571
Female981 (6.9)839 (20.5)115 (13.2)156 (27.3)
Current smokers3203 (22.6)493 (12.0)118 (13.5)42 (7.4)
Previous stroke296 (2.1)170 (4.1)40 (4.6)48 (8.4)
Known coronary disease6492 (45.7)3018 (73.6)660 (75.6)500 (87.6)
Known hypertension3914 (27.6)1905 (46.5)400 (45.8)343 (60.1)
Previous angina6722 (47.4)2524 (61.6)601 (68.8)326 (57.1)
Using antihypertensive medication6896 (48.6)3158 (77.0)661 (75.7)504 (88.3)
Previous MI6017 (42.4)2805 (68.4)609 (69.8)464 (81.3)
Previous unstable angina2159 (15.2)797 (19.4)193 (22.1)102 (17.9)
Pravastatin use7135 (50.3)2024 (49.4)429 (49.1)290 (50.8)
Age (yr)56.8 ± 7.962.0 ± 8.060.0 ± 7.964.2 ± 7.0
Systolic BP (mmHg)132.9 ± 18.0134.5 ± 19.7135.0 ± 18.9137.9 ± 20.1
Diastolic BP (mmHg)81.6 ± 10.680.5 ± 10.980.1 ± 10.879.1 ± 11.0
Weight (kg)78.3 ± 12.278.4 ± 13.584.4 ± 15.783.2 ± 15.7
BMI (kg/m2)26.4 ± 3.626.9 ± 4.028.7 ± 5.028.9 ± 4.6
Serum creatinine (mg/dl)1.0 ± 0.11.3 ± 0.21.0 ± 0.21.3 ± 0.2
MDRD-GFR (ml/min per 1.73 m2)78.1 ± 12.956.5 ± 10.379.9 ± 15.757.9 ± 12.7
Total cholesterol (mg/dl)239.5 ± 38.1223.5 ± 32.9215.0 ± 33.3212.5 ± 25.6
HDL cholesterol (mg/dl)40.5 ± 9.838.4 ± 9.436.4 ± 9.036.3 ± 9.3
LDL cholesterol (mg/dl)166.1 ± 31.6152.6 ± 28.7143.6 ± 29.2140.2 ± 22.0
Triglycerides (mg/dl)158.0 ± 75.2160.9 ± 71.9175.7 ± 87.7181.1 ± 82.8
  • a Values are mean (SD) or number (%) where appropriate. P for trend across groups all are <0.001 except for pravastatin use (P = 0.76). CKD, chronic kidney disease; MI, myocardial infarction; BMI, body mass index; MDRD, Modification of Diet in Renal Disease.