Table 2.

Proteinuria, apoptosis, and selected clinical characteristics at the time of initial biopsy in patients with FSGSa

Proteinuria (g/d)Apoptosis (% Cells)
Nonnephrotic (n = 10)1.0 ± 0.44.7 ± 1.1
Nephrotic (n = 20)7.9 ± 5.1b11.1 ± 3.2b
Non-ESRD (n = 18)2.5 ± 1.66.4 ± 2.2
ESRD (n = 12)10.4 ± 5.8c12.8 ± 3.6c
White (n = 13)6.1 ± 5.98.2 ± 4.4
Minority (n = 17)5.4 ± 4.09.5 ± 4.2
  • a Those with nephrotic-range proteinuria displayed significantly greater apoptosis (bP < 0.001). Patients who subsequently developed ESRD displayed a significantly greater degree of proteinuria and apoptosis at the time of initial biopsy than those who did not (cP < 0.001). There was no significant difference between white and minority patients with regard to proteinuria (P = 0.27) or apoptosis (P = 0.43).