Adjusted relative risks of a major CHD event (myocardial infarction incidence, fatal coronary heart disease, or coronary revascularization) associated with selected CHD risk factors among ARIC study participants with CKD
| Risk Factor | Adjusted Relative Risk (95% CIa) | ||
|---|---|---|---|
| Age, Race, Genderb | Multivariate Modelc | ||
| Age, 5 yr | 1.42 (1.20–1.68) | 1.33 (1.11–1.60) | |
| Male gender | 2.68 (1.81–3.96) | 3.96 (2.52–6.21) | |
| Black | 2.06 (0.67–6.36) | 1.79 (0.55–5.85) | |
| Traditional risk factors | |||
| current smoking | 1.65 (1.01–2.67) | 1.91 (1.16–3.15) | |
| physical activity | 0.79 (0.48–1.28) | 0.79 (0.48–1.31) | |
| hypertension | 2.02 (1.27–3.22) | 1.79 (1.11–2.89) | |
| systolic BP, 20 mmHg | 1.33 (1.13–1.57) | 1.26 (1.05–1.51) | |
| BMI, 5 kg/m2 | 1.25 (1.05–1.49) | 1.16 (0.97–1.39) | |
| obese | 1.52 (1.02–2.28) | 1.23 (0.82–1.86) | |
| glucose, 40 mg/dl | 1.31 (1.20–1.43) | 1.26 (1.15–1.39) | |
| diabetes | 3.06 (2.01–4.67) | 2.88 (1.85–4.47) | |
| total cholesterol, 43 mg/dl | 1.50 (1.25–1.79) | 1.46 (1.25–1.70) | |
| HDL cholesterol, 17 mg/dl | 0.79 (0.62–1.01) | 0.93 (0.73–1.19) | |
| log triglycerides, 0.5 log (mg/dl) | 1.38 (1.15–1.65) | 1.12 (0.94–1.33) | |
| Nontraditional risk factors | |||
| waist circumference, 13 cm | 1.38 (1.13–1.69) | 1.24 (1.00–1.55) | |
| log Lp(a), 1.2 log (mg/L) | 1.24 (0.98–1.58) | 1.20 (0.94–1.53) | |
| apolipoprotein-A1, 31 mg/dl | 0.88 (0.70–1.12) | 0.99 (0.78–1.26) | |
| apolipoprotein-B, 29 mg/dl | 1.33 (1.13–1.56) | 1.28 (1.10–1.49) | |
| anemia | 1.96 (1.14–3.36) | 2.01 (1.19–3.42) | |
| leukocyte count, 1.9 × 109 cells/L | 1.24 (1.06–1.46) | 1.10 (0.91–1.34) | |
| serum albumin, 0.332 mg/dl | 0.65 (0.54–0.79) | 0.76 (0.63–0.92) | |
| fibrinogen, 69 mg/dl | 1.38 (1.19–1.59) | 1.23 (1.07–1.41) | |